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Synonyms : | Plaet Factor-4, CXCL4, Oncostatin A, Ironplact | ||||||||||||||||||||
Description : | PF-4 is a CXC chemokine that is expressed in megakaryocytes and stored in the alpha-granules of plaets. PF-4 is chemotactic towards neutrophils and monocytes and has been shown to inhibit angiogenesis. Recombinant human PF-4 is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved residues present in CXC chemokines. | ||||||||||||||||||||
Catalog #: | 300-16 | ||||||||||||||||||||
Source : | E.coli | ||||||||||||||||||||
Stability : | The lyophilized protein is stable for at least 2 years from date of receipt at -200C. Reconstituted PF-4 is stable for at least 3 months when stored in working aliquots with a carrier protein at -200C. Avoid repeated freeze/thaw cycles. | ||||||||||||||||||||
Purity : | Greater than 98% by SDS-PAGE gel and HPLC analyses. | ||||||||||||||||||||
Endotoxin Level : | Endotoxin level is less than 0.1 ng per µg (1EU/µg). | ||||||||||||||||||||
Biological Activity : | Determined by its ability to chemoattract human fibroblasts using a concentration range of 1.0-10.0 ng/ml. | ||||||||||||||||||||
AA Sequence : | EAEEDGDLQC LCVKTTSQVR PRHITSLEVI KAGPHCPTAQ LIATLKNGRK ICLDLQAPLY KKIIKKLLES | ||||||||||||||||||||
Country of Origin : | USA | ||||||||||||||||||||
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